US

Doctors have hailed a “new era” of medicine after a study showed for the first time that a drug can slow the debilitating symptoms of Alzheimer’s. Results from the clinical trial also revealed that the drug lecanemab cleared clumps of a protein called amyloid – thought to be a key cause of the most common

A woman who was abducted when she was a baby has been reunited with her family 51 years later. Melissa Highsmith went missing in 1971 when, at just 22 months old, she was taken by a babysitter from her parents’ Fort Worth, Texas, home. Melissa’s mother Alta Apantenco was working as a waitress and in

Former US vice president Mike Pence has criticised Donald Trump for dining with a Holocaust-denying white nationalist and the rapper formerly known as Kanye West. Mr Pence is among a number of Republicans calling on the former US president to apologise for what he has described as “profoundly poor judgement”. The group – Mr Trump,

An avowed white supremacist who carried out a deadly mass shooting at a supermarket in Buffalo has pleaded guilty to murder and hate-motivated terror charges. Payton Gendron, 19, drove for three hours from his home near Binghamton, New York state, to the Tops Friendly Markets store in Buffalo, where he opened fire with an AR-15-style

At some point in our lives most of us have done something to upset someone. That person might have responded by politely asking you not to do it again, or they may have decided life is too short and simply let it go. If you’re lucky they won’t have responded by paying a hitman thousands

Irene Cara, the singer best known for the title tracks of Fame and Flashdance, has died aged 63. Her publicist said she had died in her Florida home and that the cause of death was unknown. Cara won an Oscar for the song Flashdance… What A Feeling from the 1980s hit movie Flashdance and has

Elon Musk says he would support Republican Ron DeSantis if the Florida governor runs in the 2024 US presidential election race. Mr DeSantis was re-elected with nearly 60% of the vote in the midterms and has been tipped as a potential candidate to be the next US leader. Musk’s apparent endorsement of Mr DeSantis comes

A teenager has been denied permission to witness her father die by lethal injection in Missouri after a judge upheld a law that states she is too young. Kevin Johnson, 37, faces execution on Tuesday, 29 November for shooting a police officer in 2005, when he was 19. His daughter, Corionsa “Khorry” Ramey, was two

The gunman in the Walmart mass shooting in Virginia left a “death note” addressed to God on his phone, police say. Andre Bing, 31, said that his actions were not planned, but things had fallen into place like he was being led by Satan, in the rambling note that was released by the Chesapeake Police Department

Adidas is launching an investigation into allegations of misconduct against Kanye West, including claims he showed pornography and explicit images of Kim Kardashian to staff members. The German sportswear giant, which ended its partnership with the rapper last month, said it received an anonymous letter containing several allegations against the rapper. The independent probe follows

“Soccer’s coming home,” they sing, to the tune of the Skinner and Baddiel classic. It’s a chant of choice for American fans ahead of the World Cup showdown, poking fun at their English opponents. We heard it from the crowd watching the University of Maryland take on Fairleigh Dickinson University. The gag is, of course,

Police mugshots of the suspect in the attack on a Colorado LGBTQ venue have been released after the accused appeared in court for the first time. The images of Anderson Lee Aldrich, who was arrested in the aftermath of the mass shooting at the Q Club venue in Colorado Springs, were released by the city’s

The US Supreme Court has paved the way for the handover of former president Donald Trump’s tax returns to Congress after a three-year legal battle. The court rejected Mr Trump’s emergency application for an order that would have prevented the Treasury department from giving six years of tax returns for him and some of his

Six people have been killed after a Walmart employee opened fire at a store in Virginia. Police said a seventh person who died is believed to have been the gunman and four more victims are in hospital. It happened in the city of Chesapeake, with police called shortly after 10pm local time, spokesman officer Leo

Several people have died and others injured after a Walmart manager allegedly opened fire at a store in Virginia, witnesses have said. It happened in the city of Chesapeake, with police called shortly after 10pm local time, spokesman officer Leo Kosinski said. “Chesapeake Police confirm an active shooter incident with fatalities at the Walmart on

Manchester United Football Club could finally be sold by its American owners after a 17-year reign dominated by fan protests and declining on-pitch performance. Sky News can exclusively reveal that the Glazer family is preparing to formally announce its intention to examine potential sources of outside investment that could include a full-blown auction of arguably